Khayyam Mirzazadeh was born in Baku.

He studied at the Azerbaijan State Conservatory (1957, class of Gara Garayev).

Since 1957, he has worked at the Conservatory (now the Baku Academy of Music), being the head of the Composition Department (1969-1983).

He composed music for more than 30 films, 15 dramas, pop and jazz plays, and popular songs. He has symphonies, string quartets, and symphonic suites. Among his works are the ballet “Whites and Blacks”, symphonies I and II, the symphonic poem “Essays – 63”, “Memory”, “Moroccan Rhapsody”, “Concert Piece”, concerto for violin and orchestra, etc.

Khayyam Mirzazadeh, a two-time State Prize laureate (1975, 1986), laureate of the USSR Young Composers Competition (1962), Honored Artist (1972), People's Artist (1987), Professor (1979), and awarded the Orders of "Glory" (2000) and "Honor" (2010), passed away in 2018 and was buried in the II Alley of Honor.